|   | 
  ESA Use N=4,288 | 
  No ESA Use N=8,245 | 
  p value | 
    
   
  | Female, (%)  | 
  3,606 (84) | 
  6,622 (80) | 
  <0.001 | 
    
   
  | Age (years), (SD)  | 
  42.2 (14.8) | 
  39.9 (14.9)  | 
  0.85 | 
    
   
  | Race, (%) | 
    
   
  | African American | 
  1,912 (44) | 
  4,269 (52) | 
  <0.001 | 
    
   
  | White | 
  2,047 (48) | 
  3,500 (42) | 
    
   
  | Asian | 
  286 (7) | 
  397 (5) | 
    
   
  | Native American | 
  43 (1) | 
  79 (1) | 
    
   
  | Ethnicity, (%) | 
    
   
  | Hispanic | 
  637 (15) | 
  1,394 (17) | 
  0.003 | 
    
   
  | BMI (kg/m2), (%)  | 
    
   
  | Underweight BMI<18 | 
  360 (8)  | 
  594 (7)  | 
  0.001 | 
    
   
  | 18-25 | 
  1,890 (44)  | 
  3,470 (42)  | 
    
   
  | Overweight/Obesity BMI>25 | 
  2,038 (48)  | 
  4,181 (51)  | 
    
   
  | Serum albumin (mg/dl), (%) | 
    
   
  | ≤2.5 | 
  988 (23)  | 
  2,864 (35)  | 
  <0.001 | 
    
   
  | 2.6-3.2 | 
  1,389(32)  | 
  2,745 (33)  | 
    
   
  | ≥ 3.3 | 
  1,911(45)  | 
  2,636 (32)  | 
    
   
  | Hemoglobin (mg/dl), (%) | 
    
   
  | ≤8.5 | 
  1,132 (26)  | 
  2, 926 (36)  | 
  <0.001 | 
    
   
  | 8.6-10 | 
  1,445 (34)  | 
  2,734 (33)  | 
    
   
  | ≥10 | 
  1,711(40)  | 
  2,585 (31)  | 
    
   
  | eGFR (ml/min), (%)  | 
    
   
  | ≤5.0 | 
  926 (22)  | 
  1,898 (23)  | 
  0.003 | 
    
   
  | 5.0-10.0  | 
  2,400 (56)  | 
  4,352 (53)  | 
    | 
    
   
  | ≥10.0 | 
  962 (22)  | 
  1,995 (24)  | 
    | 
    
   
  | Medical insurance type, (%) | 
    
   
  | Private | 
  1,438 (34)  | 
  2,266 (27)  | 
  <0.001  | 
    
   
  | Medicaid | 
  1,244 (29)  | 
  2,770 (34)  | 
    
   
  | No insurance | 
  247 (6)  | 
  1,068 (13)  | 
    
   
  | Medicare | 
  840 (20)  | 
  1217 (15)  | 
    
   
  | Employment at ESRD onset, (%) | 
    
   
  | Employed  | 
  984 (23)  | 
  1,477(18)  | 
  <0.001 | 
    
   
  | Unemployed  | 
  3,304 (77)  | 
  6,768 (82)  | 
    
   
  | U.S. region of residence, (%) | 
    
   
  | Northeast | 
  830 (20)  | 
  1,249 (15)  | 
  <0.001  | 
    
   
  | West | 
  817 (19)  | 
  1,573 (19)  | 
    
   
  | South | 
  1,723 (41)  | 
  3,721 (40)  | 
    
   
  | Midwest | 
  857 (20)  | 
  1,572 (19)  | 
    
   
  | Comorbidities, (%) | 
    
   
  | Hypertension | 
  3,469 (81)  | 
  6,173(74)  | 
  <0.001  | 
    
   
  | Coronary artery disease | 
  372 (9)  | 
  473(6)  | 
  <0.001  | 
    
   
  | Peripheral vascular disease | 
  176 (4)  | 
  241(3)  | 
  <0.001  | 
    
   
  | Diabetes mellitus  | 
  399 (9)  | 
  724(9)  | 
  0.32  | 
    
   
  | Congestive heart failure  | 
  631 (15)  | 
  1,327(16)  | 
  0.04  | 
    
   
  | Chronic obstructive pulmonary disease | 
  106 (2)  | 
  189(2)  | 
  0.52  | 
    
   
  | Cerebrovascular accident | 
  251 (39)  | 
  398(5)  | 
  0.01  | 
    
   
  | Current smoking  | 
  153 (4) | 
  342 (4) | 
  0.11 | 
    
   
  | IV Drug abuse | 
  17 (0.4) | 
  78 (1) | 
  <0.001 | 
    
   
  | Cancer | 
  81 (2) | 
  108 (1) | 
  0.01 | 
    
  
 *t-test for age and Chi-squared tests for categorical variables comparing LN ESRD
 patients receiving vs. not receiving ESA. |