| Extra-intestinal manifestations | 
        Healthy controls (n=21) | 
        cases with UC (n=38) | 
        Cases with CD (n=16) | 
        P (Fisher's exact) comparing: | 
       
      
        | N | 
        % | 
        N | 
        % | 
        N | 
        % | 
        UC to Healthy | 
        CD to Healthy | 
        UC to CD | 
       
      
        | Arthralgia | 
        0 | 
        0.0 | 
        14 | 
        36.8 | 
        4 | 
        25.0 | 
        <0.001 | 
        0.028 | 
        0.53[NS] | 
       
      
        | Dermatol. problems | 
        0 | 
        0.0 | 
        6 | 
        15.8 | 
        0 | 
        0.0 | 
        0.08[NS]*  | 
        **  | 
        0.16[NS] | 
       
      
        | Positive test results | 
       
      
        | s.HLA-G | 
        0 | 
        0.0 | 
        18 | 
        47.4 | 
        16 | 
        100.0 | 
        <0.001 | 
        <0.001 | 
        <0.001 | 
       
      
        | Anti-Elastase | 
        0 | 
        0.0 | 
        24 | 
        63.2 | 
        16 | 
        100.0 | 
        <0.001 | 
        <0.001 | 
        0.005 | 
       
      
        | Anti-Cathepsin-G  | 
        0 | 
        0.0 | 
        21 | 
        55.3 | 
        4 | 
        25.0 | 
        <0.001 | 
        0.028 | 
        0.07[NS] | 
       
      
        | Anti-lysozyme | 
        2 | 
        9.5 | 
        2 | 
        5.3 | 
        7 | 
        43.8 | 
        0.61[NS] | 
        0.024 | 
        0.002 | 
       
     
[NS]: Not Significant; **Incomparable. |