Figure 7: Uptake of Aβ1-42 by human primary astrocytes or microglia as measured by FACS in the presence of IRAK-1/4 inhibitor I. Cells that have internalized fluorescent labelled Aβ1-42 are expressed as percentage of the total number of cells counted using FACS (y-axis). Human astrocytes and human microglia were incubated for 24 hours with fluorescently labelled fibrillar Aβ1-42 (F-Aβ-1-42) or oligomeric Aβ1-42 (O-Aβ1-42) with or without IRAK inhibitor I (2500 nM). Results are expressed as mean (± SD) of three separate experiments.