| |
|
Healthy donors |
Headandneck cancer |
Lung cancer |
Colorectal carcinoma |
Pancreatic cancer |
Glioblastoma |
Hematological malignancies |
| Number (n) |
|
114 |
23 |
22 |
44 |
46 |
30 |
32 |
| Gender (M/F) |
|
67/47 |
21/2 |
16/6 |
26/18 |
26/20 |
14/16 |
25/7 |
| Age |
Mean |
42.9 |
62.5 |
66.1 |
64.2 |
69.8 |
56.2 |
41.7 |
| |
Range |
20-74 |
36-83 |
48-88 |
29-81 |
44-90 |
25-77 |
19-64 |
| |
SD |
14.6 |
12.2 |
10.3 |
13.0 |
40.6 |
14.1 |
12.2 |
| |
Median |
41.5 |
61.0 |
66.5 |
67.5 |
73.0 |
59.0 |
42.0 |
| lipHsp70 ELISA |
Mean Hsp70 (ng/ml) |
6.4 |
12.4 |
16.8 |
11.0 |
14.8 |
67.6 |
11.1 |
| |
SD |
2.7 |
6.1 |
16.2 |
5.2 |
7.3 |
37.5 |
9.0 |
| ROC |
AUC (CI 95 %) |
- |
0.80 |
0.78 |
0.81 |
0.86 |
0.92 |
0.62 |
| |
p-value |
- |
<0.0001 |
<0.0001 |
<0.0001 |
<0.0001 |
<0.0001 |
0.03 |
| |
Sensitivity (%) |
- |
78 |
73 |
70 |
85 |
90 |
41 |
| |
Specificity (%) |
- |
75 |
75 |
75 |
75 |
75 |
75 |
|
| Abbreviations: AUC:Area Under the Curve; M:Male; F:Female; CI:Confidence Interval; ROC:Receiver Operating Characteristic; SD:Standard Deviation |
| Table 2: Age, gender and Hsp70 levels of healthy donors and patients. |
