Figure 6: Higher frequency of CCR5+ mDCs in HIV-1/HCV co-infected individuals, but they are downregulated in response to treatment. PBMCs isolated from seronegative controls, NRs and SVRs were stained with polychromatic antibody cocktail described in supplementary Figure 1. (A) Box and whiskers graph indicating the percentage of mDCs expressing CCR5 in NRs, and (B) SVRs prior to and during the course of IFN/RBV treatment. (C) Box and whiskers graph indicating the percentage of pDCs expressing CCR5 in NRs, and (D) SVRs prior to and during the course of IFN/RBV treatment. P values were calculated using Student’s t test (* represents P<0.05; ** represents P<0.01).