Parameter |
Non-depressed |
Depressed (Mild-Moderate/Severe) |
p value |
Number of subjects (M/F) |
10 (6/4) |
13 (10/3) |
- |
Agea |
53.1 (40-69) |
48.5 (41-61) |
0.208c |
Assessment of depressionb |
1.9 ± 1.29 |
11.2 ± 4.71 |
< 0.0001c* |
CD4+ T cells (current) (cells/µl)b |
466.5 ± 212.95 |
461.4 ± 252.2 |
0.879c |
Viral load (copies/mL)a |
196 (20 - 1,116) |
4,616.7 (20 - 41,223) |
0.624c |
% undetectable |
20% |
26% |
HCV co-infection |
40% |
69% |
0.102d |
HCV viral load (IU/mL)a |
2.78 x 106 (7.93 x 104 – 5.02 x 106) |
2.03 x 106 (2.84 x 105 – 6.10 x 106) |
1.00c |
ALT (IU/L)a |
25.0 (17-36) |
61.0 (7-169) |
0.042c* |
AST (IU/L)a |
33.3 (15-51) |
53.3 (13-114) |
0.649c |
Self-reported adherence (%)b |
96.0% ± 0.02% |
85.4% ± 19.5% |
0.041c* |
Transmission (%) |
60.0% Heterosexual |
53.8% Heterosexual |
1.00d |
|
aValues are expressed as mean (range)
bValues are expressed as mean ± standard deviation
cDifferences between groups were assessed with 2-sided Wilcoxon-Mann-Whitney test
dDifferences between groups were assessed with 2-sided Fisher’s Exact Test
*p < 0.05, statistically significant difference
ALT: Alanine Transaminase; AST: Aspartate Aminotransferase |
Table 1: Demographic and Clinical Characteristics of HIV Positive Subjects in the Study. |