|
Mouse |
Human |
FcγR |
FcγRI |
FcγRIIRB |
FcγRIII |
FcγRIV |
FcγRIA |
FcγRIIA |
FcγRIIB |
FcγRIIC |
FcγRIII A |
FcγRIIIB |
Signalling pathways |
ITAM FcR-γ |
ITAM |
ITAM FcR-γ |
ITAM FcR-γ |
ITAM FcR-γ |
ITAM |
ITAM |
ITAM |
ITAM FcR-γ |
|
affinity |
High |
Low |
Low |
Low |
High |
Low |
Low |
Low |
Low |
Low |
monocytes/macrophages |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
− |
+ |
− |
Neutrophils |
+ |
+ |
+ |
+ |
+ |
+ |
+ |
− |
− |
+ |
Dentritic cells |
+ |
+ |
+ |
− |
+ |
+ |
+ |
− |
+ |
− |
B cells |
− |
+ |
− |
− |
− |
− |
+ |
− |
− |
− |
Mast cells |
− |
− |
− |
− |
− |
− |
+ |
− |
− |
+ |
|
