Figure 3: CMV-specific IFNγ-production and proliferative capacity. A. IFNγ-production by CD4+ and CD8+ T cells in response to pp65 or IE1 in patients with and without CMV-reactivation after SCT were measured by ICCS. Presented are the maximum T-cell responses within one year post-SCT. The median is indicated by a straight line. B. Proliferative capacity of CD4+ and CD8+ T cells in response to pp65 or IE1 was measured by CFSE-labelling. At each time point SI was determined and categorized into good (S.I.>2.0), intermediate (1.5<S.I.<2.0)or no proliferative capacity (S.I.<1.5). Presented is the percentage of patients with most responses after SCT in the represented category. Good proliferative capacity S.I.>2.0, black; Intermediate proliferative capacity 1.5<S.I.<2.0, grey; No proliferative capacity S.I.<1.5, white.