| Pro-atheroscleotic genes |
Effect of Ang II |
| monocyte chemotactic protein-1 (MCP-1) |
upregulation |
| macrophage-colony stimulating factor (M-CSF) |
upregulation |
| endothelial-selectin (E-selectin) |
upregulation |
| intercellular adhesion molecule-1 (ICAM-1) |
upregulation |
| vascular cell adhesion molecule-1 (VCAM-1) |
upregulation |
| inducible nitric oxide synthase (iNOS) |
upregulation |
| cyclooxygenase-2 (COX-2) |
upregulation |
| tumor necrosis factor-α (TNF-α) |
upregulation |
| interleukin-6 (IL-6) |
upregulation |
| interleukin-1β (IL-1β) |
upregulation |
| transforming growth factor β1 (TGF-β1) |
upregulation |
| regulated upon Activation, Normal T cell Expressed and Secreted (RANTES) |
upregulation |
| monocyte chemoattractant protein-1 (MCP-1) |
upregulation |
| C-C chemokine receptor type 1 (CCR1) |
upregulation |
| C-C chemokine receptor type 2 (CCR2) |
upregulation |
| C-C chemokine receptor type 3 (CCR3) |
upregulation |
| granulocyte colony-stimulating factor (G-CSF) |
upregulation |
| granulocyte macrophage colony-stimulating factor (GM-CSF) |
upregulation |
| interleukin-12 IL-12 (P40) |
upregulation |
| macrophage inflammatory protein 1-α (MIP-1α) |
upregulation |
| interferon-γ (IFN-γ) |
upregulation |
| Anti-atheroscleotic genes |
Effect of Ang II |
| peroxisome proliferator-activated receptor-α (PPAR-α) |
downregulation |
| peroxisome proliferator-activated receptor-γ (PPAR-γ) |
downregulation |
