Case No. Patient Site Clinical features Laboratory studies/CST* Treatment Outcome
1 35 yo man, teacher in rural area Cadereyta, Nuevo Leon state. Left preauricular region. Trauma of his fingernails. Epidermal cyst-like lesion. Regional LAD+ Incidental finding at skin biopsy. Chest X-ray normal. CST+ Excision and oral itraconazole 400 mg/day for 4 months Resolution in 20 weeks.
2 65 yo man, goat-farmer from Dr. Coss, Nuevo Leon state Left preauricular region. Trauma of his fingernails. Epydermal cyst-like lesion. Regional LAD+ Incidental finding at skin biopsy. Chest X-ray normal. CST+ Exicision and Itraconazole 400 mg/day for 6 months Resolution in 36 weeks
3 32 yo woman who visited a rural area in northern Nuevo Leon state. Nose and cheeks affected. Treated as Rosacea with minocycline 200 mg/day for 3 months. No history of trauma Rosacea-like lesions. LAD- Incidental finding at skin biopsy. Chest X-ray normal. CST+ Oral Itraconazole 400 mg/day for 4 months Resolution in 14 weeks
4 68 yo man, cattle herder in Torreon, Coahuila state. Dorsum of left hand. Trauma with barbed wire. Verrucose tuberculosis, Sporotricosis, vs. Orf. LAD+ Incidental finding at skin biopsy. Chest X-ray normal. CST+ CF 1:128 Culture + Oral itraconazole 300 mg/day for 8 months Resolution in 10 months, CF 1:8.
5 38 yo male farmer from Tijuana. Trauma of left forearm with cactus thorn in Anaheim, CA. Sporotrichosis, verrucose tuberculosis LAD+ Incidental finding at skin biopsy. Chest X-ray normal. CST+ CF 1:128 Culture + Oral itraconazole 300 mg/day for10 months Resolution in 12 months CF1:8
Table 1: Summary of the 5 cases with Primary Cutaneous Coccidioidomycosis. YO, Years old; LAD, lymphadenopathy; CST, coccidioidin skin test; CF, coccidioidin-fixation test.