Figure 2: Histopathologic features of mouse dorsal skin. a) Anagen: After depilation 12days, hair has reached the depths of fat tissue (hematoxylin-eosin). b) Anagen: After depilation 12days, stained layer is outer root sheath, not hair bulb (MT1-antibody). c) Anagen: After depilation 8 days, a thick layer of outer root sheath is observed on hair cross section (hematoxylin-eosin). d) Anagen: After depilation 8 days, it is stained in accordance with the thick outer root sheath (MT1-antibody).