Adverse event Total (n=12) Grade 1 Grade 2 Grade 3 Grade 4 Anemia 6 (50.0) 3 (25.0) 3 (25.0) 0 0 Edema 1 (8.3) 0 1 (8.3) 0 0 Nausea 2 (16.7) 0 2 (16.7) 0 0 Neutropenia 8 (66.7) 2 (16.7) 5 (41.7) 1 (8.3) 0 Palpitations 1 (8.3) 1 (8.3) - - - Pulmonary fibrosis 1 (8.3) 1 (8.3) 0 0 0 Thrombocytopenia 2 (16.7) 2 (16.7) 0 0 0

Table 3: Toxicity in taxane-based chemotherapy. Values represent the number of adverse events (%).