Figure 1: Fgure shows a female, 46 years old, has suffered from middle to severe melasmaon the whole face for 10 years, after receiving 12 weekly Q-switchedNd:YAG laser treatments (3.5 J/cm2, 6 mm spot size, 2-3 passes) for melasma, the multiple hypopigmented–depigmented macules interspersed with mottled hyperpigmented macules appeared, which is difficult to repair at 2 years’ follow up.