| Features |
Familial Melanoma (N=62) |
Non Familial Melanoma (N=127) |
P |
CI 95% |
OR |
| Age: Mean (SD) |
55.47 (15.980) |
66.60 (18.042) |
0 |
6.016-16.255 |
|
| Sex: Men |
24 (38.7%) |
64 (50.4%) |
0.131 |
|
|
| Women |
38 (61.3%) |
63 (49.6%) |
|
|
|
| Age at diagnosis |
|
|
0 |
7.226-18.004 |
|
| Mean (SD) |
44.26 (17.198) |
56.87 (18.267) |
|
|
|
| Melanoma site |
|
|
0.01 |
|
|
| -head/neck |
4 (6.5%) |
20 (15.7%) |
|
|
|
| -upper limbs |
6 (9.7%) |
15 (11.8) |
|
|
|
| -lower limbs |
19 (30.6%) |
17 (13.4%) |
|
|
|
| -palms |
0 (0%) |
10 (7.9%) |
|
|
|
| -soles |
7 (11.3%) |
19 (15%) |
|
|
|
| -trunk |
26 (41.9%) |
46 (36.2%) |
|
|
|
| Breslow thickness: Mean (SD) |
0.79 (1.634) |
2.34 (3.79) |
0.021 |
0.169-2.37 |
|
| MM in situ |
22 (35.5%) |
25 (19.7%) |
0.018 |
1.111-2.485 |
1.662 |
| Histological subtype |
|
|
0.031 |
|
|
| -LMM |
3 (4.8%) |
11 (8.7%) |
|
|
|
| -SSM |
51 (82.3%) |
78 (61.4%) |
|
|
|
| -NM |
1 (1.6%) |
10 (7.9%) |
|
|
|
| -ALM |
7 (11.3%) |
28 (22%) |
|
|
|
| Multiple Melanomas |
20 (32.3%) |
19 (15%) |
0.006 |
1.229-2.730 |
1.832 |
| Past history of sunburns |
35 (87.5%) |
50 (61.7%) |
0.004 |
1.264-6.951 |
2.965 |
| Intense solar exposure before 18year |
18 (45%) |
18 (21%) |
0.006 |
1.063-2.132 |
1.506 |
|
