| Features |
CDKN2A Melanoma(N=17) |
Non CDKN2A Melanoma (N=168) |
P |
CI 95% |
OR |
| Age: Mean (SD) |
49.53 (12.674) |
64.29 (17.973) |
0 |
7.782-21.731 |
|
| Sex: Men |
6 (35.3%) |
80 (47.3%) |
0.342 |
|
|
| Women |
11 (64.7%) |
89 (52.7%) |
|
|
|
| Age at diagnosis |
|
|
0 |
8.567-24.402 |
|
| Mean (SD) |
37.71 (14.581) |
54.19 (18.502) |
|
|
|
| Melanoma site |
|
|
0.015 |
|
|
| -head/neck |
0 (0%) |
23 (13.6%) |
|
|
|
| -upper limbs |
1 (5.9%) |
19 (11.2%) |
|
|
|
| -lower limbs |
8 (47.1%) |
28 (16.6%) |
|
|
|
| -palms |
0 (0%) |
10 (5.9%) |
|
|
|
| -soles |
0 (0%) |
26 (15.4%) |
|
|
|
| -trunk |
8 (47.1%) |
63 (37.3%) |
|
|
|
| Breslow thickness: Mean (SD) |
0.74 (0.532) |
2.12 (3.490) |
0 |
0.823-1.910 |
|
| MM in situ |
10 (58.8%) |
36 (21.3%) |
0.002 |
1.756-10.765 |
4.348 |
| Histological subtype |
|
|
0.031 |
|
|
| -LMM |
0 (0%) |
14 (8.3%) |
|
|
|
| -SSM |
17 (100%) |
109 (64.5%) |
|
|
|
| -NM |
0 (0%) |
11 (6.5%) |
|
|
|
| -ALM |
0 (0%) |
35 (20.7%) |
|
|
|
| Multiple Melanomas |
11 (64.7%) |
28 (16.6%) |
0 |
2.727-17.513 |
6.91 |
| Past history of sunburns |
7 (100%) |
76 (67.9%) |
0.1 |
|
|
| Intense solar exposure before 18year |
8 (80%) |
27 (23.9%) |
0.001 |
|
|
|
