| Patients with vitiligo (n=11) |
| Populations of cells |
Healthy Volunteers (n=10) |
Lesional Skin |
Marginal Skin |
Normally Pigmented Cells |
P |
P1 |
P2 |
| Edipdermis (cells) |
| СD4+ |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.0) |
- |
- |
- |
| CD8+ |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.2) |
0.0 (0.0; 0.2) |
0.0 (0.0; 0.2) |
0.017 |
0.083 |
0.082 |
| CD4+/СD8+ |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.0) |
- |
- |
- |
| CD83+ |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.0) |
0.0 (0.0; 0.0) |
- |
- |
- |
| CD1a |
9.3 (8.8; 9.8) |
5.0 (3.0; 7.0) |
10.0 (9.2; 11.0) |
10.0 (9.0; 10.8) |
0.002 |
0.147 |
0.322 |
| Derma (percent) |
| CD4+ |
6.0(5.0; 8.0) |
10.0 (8.0; 14.0) |
11.0 (8.0; 13.0) |
10.0 (7.0; 12.0) |
0.005 |
0.003 |
0.007 |
| CD8+ |
9.0(7.0; 13.0) |
21.0 (17.0;26.0) |
22.0 (21.0; 28.0) |
23.0 (20.0;24.0) |
0 |
0.001 |
0 |
| CD4+/CD8+ |
0.65 (0.60; 0.71) |
0.47 (0.33; 0.84) |
0.50 (0.33; 0.59) |
0.42 (0.40; 0.55) |
0.105 |
0.006 |
0.001 |
| CD83+ |
6.5 (6.0; 10.0) |
22.0 (9.0; 26.0) |
21.0 (8.0; 22.0) |
21.0 (9.0; 26.0) |
0.004 |
0.007 |
0.003 |
| CD1a+ |
6.5 (5.0; 8.0) |
5.0 (3.0; 7.0) |
5.0 (3.0; 6.0) |
5.0 (3.0; 6.0) |
0.188 |
0.126 |
0.155 |
Note: Р, Р1 and Р2 –levels of statistical significance when comparing indicators of healthy volunteers and patients, respectively, regarding lesional skin, marginal skin and
perilesional normally pigmented skin (Mann-Whitney U-test). |
