Figure 1A&1B: (A) Mean methylation rate in the promoter of IL-12B from psoriatic epidermis (n=30), including involved psoriatic epidermis (IP) and uninvolved psoriatic epidermis (UP), and healthy control epidermis (HC) (n=28). Compared to healthy controls, there was significantly hyper-methylated in both involved psoriatic epidermis (p0.001) and uninvolved psoriatic epidermis (p=0.009). The methylation rate of IL-12B in uninvolved psoriatic epidermis is lower than that in involved psoriatic epidermis (p=0.031).(B) Methylation status in the promoter of IL-12B from psoriatic epidermis (n=30), including involved epidermis and uninvolved epidermis, and healthy control epidermis (n=28).