Figure 4: Clinical photograph of a prominent mole on the back (A). This lesion shows on dermoscopy (B) multiple colors, atypical network and gray dots/ granules. CM mosaic image (C, 1 x 1 mm) at the level of the suprabasal layer shows spindle shaped cells (red arrows) and nucleated cells (yellow rectangle) infiltrating the epidermis. CM image (D, 0,75 x 1 mm) at the level of the DEJ shows junctional thickening (red arrow), non-edged papillae (yellow arrow), numerous pagetoid cells (yellow square) and dendrites (red rectangle). On histopathology (E), the lesion proved to be a melanoma.