Molecule Functions Main ligands References
ICAM-1(CD54) Leukocyte adhesion, facilitates leukocyte transmigration LFA-1 and Mac-1 [36,64,80-82]
VCAM-1(CD106) Leukocyte adhesion VLA-4 [36,80,83]
Thy-1(CD90) Leukocyte adhesion, secretion of IL-8 and MMP-9 by neutrophils Mac-1 [40]
E-selectin (CD62E) Rolling of leukocytes on blood vessels Sialyl LewisA and Sialyl LewisX [36,38,82,83]
P-selectin(CD62P) Rolling of leukocytes on blood vessels PSGL-1 [36]
Table 1: Adhesion molecules expressed by endothelial cells in psoriasis