| DIF |
-Strong, shaggy BMZ staining for IgM, C3, IgG and fibrinogen; also present in sebaceous and sweat glands and some dermal blood vessels.
-Elastic globes (DNA complexed with IgG).
-Some fibrinoid clumps in the dermis.
-Positive cytoid bodies. |
-Particulate epidermal IgG deposition (all anti-Ro/SSA positive).
|
-Positive ANA titers, as well as anti-dsDNA antibodies. Anti-Sm, anti-RNP, ENA, and anti- chromatin antibodies.
-Positive BMZ linear, shaggy and/or granular deposits with IgG, IgM, and C3, and less with fibrinogen.
-Strong reactivity to dermal vessels with most antibodies.
-Positive cytoid bodies. |
-Positive antinuclear antibodies (ANAs), antihistone antibodies and anti-Ro/SSA antibodies.
-Strong, shaggy BMZ staining with IgG, C3, and fibrinogen. |
-Strong, shaggy BMZ staining with IgM and C3.
-Strong deposits of fibrinogen in dermal vessels. |
-BMZ linear deposits with IgG and C3, and less with fibrinogen. |
-Anti-C3d in a fibrillar, interrupted linear, or granular pattern. Weak, noncontinuous deposits of IgM, C1q and IgG. |
