Gene

SNP ID

Major /Minor allele

Responder

Non-responder

Dominant model

Recessive model

Co dominant model

Major homo

Hetero

Minor homo

Major homo

Hetero

Minor homo

OR (95%CI)

P-value

OR (95%CI)

P-value

P-value

Corrected p-value*

CFH

rs800292

G/A

0.61

0.34

0.05

0.50

0.42

0.08

1.78 (0.28-11.30)

0.54

1.58 (0.63-3.93)

0.33

0.58

0.58

CFH

rs1061170

T/C

0.75

0.25

0.00

0.96

0.04

0.00

-

-

0.12 (0.015-0.94)

0.018

0.018

0.019

CFH

rs1410996

C/T

0.54

0.42

0.04

0.35

0.46

0.19

5.08 (1.12-23.08)

0.023

2.19 (0.86-5.62)

0.098

0.044

0.046

*Corrections were performed with permutation test SNP: single nucleotide polymorphism, CFH: complement factor H, OR: odds ratio, CI: coefficient interval
Table 3: Summary of the genotype association analysis with the resopnse to photodynamic therapy in polypoidal choroidal vasculopathy.