Gene |
SNP ID |
Major /Minor
allele |
Responder |
Non-responder |
Dominant model |
Recessive model |
Co dominant model |
Major homo |
Hetero |
Minor homo |
Major homo |
Hetero |
Minor homo |
OR (95%CI) |
P-value |
OR (95%CI) |
P-value |
P-value |
Corrected p-value* |
CFH |
rs800292 |
G/A |
0.61 |
0.34 |
0.05 |
0.50 |
0.42 |
0.08 |
1.78 (0.28-11.30) |
0.54 |
1.58 (0.63-3.93) |
0.33 |
0.58 |
0.58 |
CFH |
rs1061170 |
T/C |
0.75 |
0.25 |
0.00 |
0.96 |
0.04 |
0.00 |
- |
- |
0.12 (0.015-0.94) |
0.018 |
0.018 |
0.019 |
CFH |
rs1410996 |
C/T |
0.54 |
0.42 |
0.04 |
0.35 |
0.46 |
0.19 |
5.08 (1.12-23.08) |
0.023 |
2.19 (0.86-5.62) |
0.098 |
0.044 |
0.046 |
*Corrections were performed with permutation test
SNP: single nucleotide polymorphism, CFH: complement factor H, OR: odds ratio, CI: coefficient interval |