| Author |
Aphakic glaucoma eyes (numbers) |
Procedure |
Anti-metabolite dose and duration |
Success criteria |
Success rate |
| Pakravan (2007) |
15 |
Trabeculectomy + MMC |
0.2 mg/ml for 2 minutes |
IOP 5- 21 mmHg with or without medication |
33 % (without medication)
40 % (with ≤ 2 medications) |
| Chen et al (2004) |
61 |
Trabeculectomy + MMC or 5-FU (1 without anti-metabolite) |
Not specified |
IOP ≤ 21 mmHg with or without medication |
24.6% |
| Mandal et al (2002) |
21 aphakic
2 pseudophakic |
Trabeculectomy + MMC
|
0.4 mg/ml for 2-3 minutes |
IOP 6-21 mmHg with or without medication |
36.8% (without medication)
21.1% (one medication) |
| Sidoti et al (2000) |
3 |
Trabeculectomy + MMC
|
0.4 mg/ml for 1.5-8 minutes |
IOP 5-21 mmHg with medication |
66.6% |
| Azuora-Blanco et al (1999) |
8 |
Trabeculectomy + MMC
|
0.4 mg/ml for 1-5 minutes |
IOP < 21 mmHg without medication |
0% |
| Wallace et al (1998) |
13 |
Trabeculectomy + MMC
|
0.2 or 0.4 mg/ml for 4 minutes |
IOP < 26 mmHg or < 21 mmHg with medication |
62% |
| Beck et al (1998) |
9 |
Trabeculectomy + MMC
|
0.25 or 0.5 mg/ml for 5 minutes |
IOP < 22 mmHg with or without medication |
78% |
| Asrani and Wilensky (1995) |
12 |
Trabeculectomy + MMC (5 eyes without anti-metabolite) |
Not specified |
IOP < 22 mmHg |
85% |
SD, standard deviation; MMC, mitomycin C; 5-FU, 5-fluorouracil