Figure 12: Glaucoma-related stressors elevate expression of IL-6 family members in a stressor-dependent manner. Gene expression of CNTF (A), LIF (B), CLCF1 (C), CTF1 (D), OSM (E) and IL-11 (F) in whole retina from young C57, aged C57, young DBA/2 and aged DBA/2 mice, as determined by quantitative PCR. Levels of gene expression are determined by the ΔΔCT method, using GAPDH as the reference gene. Data are presented as percent change in gene expression relative to expression in young C57 retina (ΔΔCT). A-D. Asterisks denote statistical significance (p < 0.05), as compared to expression in young C57 retina. E,F. Asterisks denote statistical significance (p < 0.05), as indicated by brackets.