Thickness (μm) Healthy DM MDR
Across All Macular Regions      
RNFL   42.02 ± 2.11 41.19 ± 2.19 41.38 ± 2.93
GCL+IPL 78.30 ± 4.09 7 5.4 1 ± 5.2 3 † (-8 %)71 .80 ± 8.22 ‡
INL 35.02 ± 1.60 35.74 ± 2.13 35.05 ± 2.76
OPL 41.30 ± 2.49 (-10%)39.88 ± 5.04 ‡ (-13%)36.07 ± 3.45 ‡
ONL+IS 86.41 ± 5.21 85.55 ± 7.32 88.39 ± 8.21
OS 16.27 ± 3.06 (-20%)17.97 ± 2.64 ‡ (-11%)14.40 ± 2.20 ‡
RPE 12.71 ± 1.32 (-7%)13.78 ± 1.28 ‡ 12.76 ± 1.09
Foveal Region      
RNFL 8.85 ± 2.37 (-30%)11.83 ± 2.45 ‡ 8.30 ± 2.44
GCL+IPL 55.80 ± 3.87 67.58 ± 15.20 (+26%)70.26 ± 11.02 ‡
INL 20.93 ± 1.82 25.89 ± 4.30 (+19%)25.00 ± 4.85 ‡
OPL 61.24 ± 6.83 (-27%)53.08 ± 18.22 ‡ (-36%)38.97 ± 12.09 ‡
ONL+IS 99.26 ± 6.79 97.42 ± 8.92 100.35 ± 12.27
OS 18.05 ± 4.03 (-17%)19.53 ± 3.14 ‡ 16.22 ± 2.96 †
RPE 12.84 ± 1.72 14.06 ± 1.59 † 13.10 ± 1.32
Parafoveal Region      
RNFL 33.72 ± 1.85 (-8%)34.16 ± 1.48 ‡ (-7%)31.33 ± 5.23 ‡
GCL+IPL 94.71 ± 5.73 (-7%)92.93 ± 6.75 ‡ (-8%)86.73 ± 11.2 ‡
INL 39.60 ± 2.17 40.49 ± 2.68 39.24 ± 3.32
OPL 37.17 ± 2.68 38.15 ± 2.54 37.07 ± 2.21
ONL+IS 84.89 ± 6.11 83.24 ± 8.16 † 86.85 ± 8.35
OS 14.80 ± 3.58 (-24%)16.97 ± 2.99 ‡ 12.84 ± 2.50 †
RPE 11.57 ± 1.59 13.08 ± 1.74 † 12.02 ± 1.64
Perifoveal Region      
RNFL 41.87 ± 2.94 (-6%)41.39 ± 2.68 ‡ (-8%)38.7 ± 5.47 ‡
GCL+IPL 67.36 ± 4.52 64.39 ± 6.07 63.89 ± 8.40 †
INL 33.00 ± 1.67 33.38 ± 1.91 32.77 ± 3.12
OPL 31.54 ± 1.38 31.86 ± 1.49 31.49 ± 2.17
ONL+IS 75.27 ± 4.84 74.67 ± 7.01 † 78.01 ± 6.50 †
OS 14.59 ± 2.81 (-23%)16.45 ± 2.64 ‡ (-13%)12.72 ± 2.31 ‡
RPE 12.54 ± 1.39 13.33 ± 1.51 † 12.44 ± 1.34
† 0.001<p<0.05 and ‡ p<0.001 (ANOVA followed by Newman-Keuls post hoc analysis). For comparisons between MDR and healthy eyes (see MDR column); and between MDR and DM eyes (see DM column). Changes in percentage are indicated at the upper left of each measure SD: Standard Deviation; MDR: Mild Diabetic Retinopathy; DM: Diabetes Mellitus
Table 2: Distribution statistics of thickness (mean ± SD) by study group.