Figure 2: Accelerated corneal collagen crosslinking Group 1 (epitheliumoff): Riboflavin 0.1% plus Dextran 20%, 15 min of corneal soaking, UV-A power at 12 mW/cm2, Energy dose at 7.2 J/cm2), 10 min exposure time. Postoperative confocal scans revealed lacunar edema (upper left white arrow-a) with keratocytes apoptosis (upper right white arrow - b; bottom left white arrow-c) and increased density of extracellular matrix surrounding edema. A transition between hypo-cellular stroma and stroma unreached by the treatment (vertical transition area) is showed in bottom left - d scan with an estimated penetration depth of 180 μm (range 160-200 μm).