Control ≤55years Secondary glaucoma Previous surgery Previous topical therapy Re-do surgery Trainee surgeon
Early antifibrotic (% eyes of total) 18% 28% 35%* 29% 25% 23% 32%
Early antifibrotic (no./eye treated) 1.9 2.0 1.6 2.0 1.9 1.9 1.8
Early antifibrotic rate (mean of total) 0.34 0.56*** 0.58*** 0.54*** 0.49*** 0.42*** 0.58***
Odds Ratio 1.0 1.8 2.5* 1.9 1.5 1.3 2.1
Late antifibrotic (Phako surgery censored) (% eyes of total) 12% 10% 13% 8% 9% 11% 17%
Late antifibrotic (Phako surgery censored) (no./eye treated) 1.4 2.5 1.0 1.7 1.3 1.3 1.8
Late antifibrotic (Phako surgery censored) (mean of total) 0.20 0.25 0.16 0.13 0.12 0.13 0.44
Odds Ratio 1.0 0.81 1.11 0.63 0.70 0.93 1.47
*p<0.05, **p<0.01, ***p<0.001
Table 6b: Early and late post-operative administration of either sub-conjunctival 5-fluorouracil or trans-conjunctival mitomycin-C for the control and risk factor sub-groups.