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Figure 4: Prevention of TUNEL (+) cells by Anti-TNFα treatment. The STZ-induced diabetic mice were IP injected antibody weekly for 3 months. (A-E) The sample images of TUNEL staining for non-diabetic (A), diabetic with the treatments of PBS (B), 2 mg/kg (C), 8 mg/kg (D) and 25 mg/kg (E). (F) Quantitative results were expressed as mean ± SD (n=10). $ p<0.05 compared to non-diabetes. * p<0.05 compared to diabetes with PBS treatment. Scale bar: 100 μm. |