| Code |
Drug/lipid (wt%) |
Compositiona |
EE (wt%)b |
LC (wt%)c |
Particle size (sµm)d |
| L-1 |
10 |
PC/CH 7:3 |
90.15± 0.58 |
3.64± 0.02 |
1.30 ± 0.24 |
| L-2 |
10 |
PC/CH 6:4 |
91.0± 0.24 |
4.41± 0.01 |
0.99 ± 0.08 |
| L-3 |
10 |
PC/CH 5:5 |
90.96± 0.07 |
4.63± 0.0 |
1.29 ± 0.46 |
| L-4 |
25 |
PC/CH 7:3 |
97.27± 0.07 |
10.83± 0.0 |
1.16 ± 0.52 |
| L-5 |
50 |
PC/CH 7:3 |
98.44± 0.01 |
16.39± 0.0 |
1.35± 0.25 |
| aPhosphatidyl choline/cholesterol (PC/CH) ratio
bPercent encapsulation efficiency, calculated from equation (1), mean of three different formulations ± SD
cPercent loading capacity, calculated from equation (2), mean of three different formulations ± SD d Particle size, mean of three different formulations ± SD |
|
