Parameter Time Temperature
4°C 25°C 40°C
Drug content (%) 1 month 99.68± 0.15 99.34± 0.13 97.01± 0.17
2 months 99.37± 0.21 98.64± 0.10 95.23± 0.20
3 months 98.85± 0.19 97.37± 0.19 92.92± 0.27
Electrical conductivity [mS] 1 month 4.51 ± 0.08 4.52 ± 0.07 4.50 ± 0.06
3 months 4.52 ± 0.08 4.52 ± 0.07 4.51 ± 0.09
6 months 4.51 ± 0.06 4.52 ± 0.08 4.50 ± 0.10
Refractive index 1 month 1.442 ± 0.001 1.441 ± 0.001 1.442 ± 0.000
3 months 1.442 ± 0.002 1.442 ± 0.003 1.442 ± 0.001
6 months 1.441 ± 0.002 1.442 ± 0.001 1.442 ± 0.001
Viscosity [mPas] 1 month 22.23 ± 0.06 21.66 ± 0.23 21.94 ± 0.02
3 months 22.05 ± 0.09 22.11 ± 0.06 22.17 ± 0.08
6 months 22.43 ± 0.08 22.45 ± 0.10 22.60 ± 0.06
Considering the initial concentration of 2% w/v as 100%
Table 3: Stability results of the monitored parameters for the developed microemulsion (mean ± SD n=3).