| Patient number | 
        Age | 
        Diabetes mellitus type | 
        Duration period of DM (years) | 
        Principal therapy  DM | 
        Average compensation according    to HbA1c | 
        Type of diabetic retinopathy | 
        Type of diabetic macular edema | 
        Previous therapy of DME | 
        Concomitant diseases | 
      
      
        | 1 | 
        68 | 
        2 | 
        6 | 
        PAD | 
        5.50% | 
        Nonproliferative | 
        Diffuse | 
        3x focal laser of the macula | 
        Decompensated arterial hypertension | 
      
      
        | 2 | 
        73 | 
        2 | 
        20 | 
        INZ | 
        8% | 
        Risk nonproliferative | 
        Diffusion ischemic | 
        PRF, 4x focal laser | 
        Arterial hypertension | 
      
      
        | 3 | 
        68 | 
        2 | 
        18 | 
        INZ | 
        7.40% | 
        Nonproliferative | 
        Diffuse | 
        Incomplete GRID OPL | 
        Arterial hypertension, hyperlipidaemia | 
      
      
        | 4 | 
        77 | 
        2 | 
        19 | 
        INZ | 
        8.20% | 
        Nonproliferative | 
        Diffuse | 
        Incomplete GRID OPL | 
        Arterial hypertension, hyperlipidaemia, stroke | 
      
      
        | 5 | 
        56 | 
        2 | 
        10 | 
        PAD | 
        9.40% | 
        Nonproliferative | 
        Focal | 
        3x focal laser of the macula | 
        Asthma | 
      
      
        | 6 | 
        82 | 
        2 | 
        25 | 
        INZ | 
        6.50% | 
        Risk nonproliferative | 
        Diffuse | 
        2x focal laser of the  macula, incomplete PRF | 
        Arterial hypertension, hyperlipidaemia | 
      
      
        | 7 | 
        69 | 
        1 | 
        30 | 
        INZ | 
        10% | 
        Proliferative | 
        Diffuse | 
        PRF left | 
        Arterial    hypertension, ischemic heart disease, peripheral arterial disease, right    lower limb amputation | 
      
      
        | 8 | 
        57 | 
        2 | 
        7 | 
        PAD | 
        6.80% | 
        Nonproliferative | 
        Diffuse | 
        3x focal laser of the macula, 4x study medication    (Ozurdex/placebo) | 
        0 | 
      
      
        | 9 | 
        56 | 
        2 | 
        10 | 
        PAD+INZ | 
        9.30% | 
        Proliferative | 
        Focal | 
        PRF | 
        Arterial hypertension | 
      
      
        | 10 | 
        70 | 
        2 | 
        24 | 
        PAD | 
        5.60% | 
        Nonproliferative | 
        Focal | 
        1x focal laser of the macula | 
        Ischemic heart disease | 
      
      
        | 11 | 
        45 | 
        1 | 
        30 | 
        INZ | 
        5.60% | 
        Risk nonproliferative | 
        Diffuse | 
        2x focal laser of the macula, incomplete PRF | 
        Arterial hypertension, frequent hypoglycaemias | 
      
      
        | 12 | 
        75 | 
        2 | 
        19 | 
        INZ | 
        6.20% | 
        Nonproliferative | 
        Diffuse | 
        2x focal laser of the macula | 
        Arterial hypertension, hyperlipoproteinaemia,    operation of valvular defect | 
      
      
        | 13 | 
        65 | 
        2 | 
        25 | 
        INZ | 
        8.50% | 
        Nonproliferative | 
        Focal | 
        2x focal laser of the macula | 
        Arterial hypertension, heavy obesity, 
          diabetic foot |