| Causes of POGS |
Specific features |
Treatment |
| Cat scratch disease
(B. henselae/A. felis) |
History of contact with cats/kittens (rarely, dogs or rabbits); positive serology, biopsy |
Erythromycin/azithromycin, ciprofloxacin, gentamicin, rifampin or TMP-SMX |
| Oculoglandular tularemia
(F. tularensis) |
History of contact with rabbits, hares, squirrels, rats, mice or foxes; necrotizing conjunctival inflammation and ulceration; vomiting, pneumonia |
Streptomycin IM or gentamicin IV; topical gentamicin
|
| Conjunctivalsporotrichosis (Sporothrixschenkii) |
Hard, non-tender nodule on eyelid skin; numerous soft, granulomatous nodules that may ulcerate; biopsy,culture |
Itraconazole (systemic) |
| Conjunctival tuberculosis
(M. tuberculosis) |
History of ocular trauma; small painless conjunctival ulcers; positive tuberculin skin test, interferon gamma release assay, chest x-ray |
Isoniazid with ethambutol, rifampin or streptomycin |
| Conjunctival syphilis
(T. pallidum) |
During primary, secondary or tertiary stages of disease; diffuse, rose red, jelly-like thickening of tarsal conjunctiva; iridocyclitis; corneal pannus and perforation; panophthalmitis |
Penicillin |
| Conjunctivalcoccidiomycosis
(C. immitis, B. dermatitidis) |
Erythema nodosum, phlyctenular conjunctivitis, episcleritis, scleritis, keratoconjunctivitis or iridocyclitis |
Ketoconazole, fluconazole or itraconazole,
Amphotericin B in worsening disease |
