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Figure 5: Transmission electron microscopic images of ultra-thin sections from injected eyes. (A) Non-injected control eye section, (B) subretinal BSS-injected control eye section, (C) subretinal biopolymer-injected 1 day eye section postinjection and (D) subretinal biopolymer-injected eye section 3 weeks postinjection. RPE cells from non-injected and BSS-injected controls have long apical microvilli surrounding the photoreceptor outer segment tips. At 1 day post-injection, amorphous biopolymer “blobs” can be seen in the subretinal space adjacent the RPE in biopolymer-injected eye. 3 weeks after injection, the biopolymer has been degraded/absorbed and the RPE microvilli appear to form their normal morphology. os: Photoreceptor Outer Segment; n: Nucleus; v: RPE Microvilli; p: Biopolymer. |