Figure 1: (a) Clinical picture showing and ulcerated lesion located in the upper eyelid. The lesion extended to the palpebral conjunctiva. Madarosis and entrepion were also observed. (b) Histopathological picture of the incisional biopsy showing an intraepithelial proliferation of neoplastic cells with high-grade nuclear atypia and focal areas showing cells with vacuolated cytoplasm. Periodic-Schiff acid and alcian blue stains were negative (Hematoxilin-Eosin (H&E), 400X).