% of eyes with no change or an improvement in visual acuity Number of Eyes with a Decrease in acuity (average change in LogMar value) Number of Eyes with no change in visual acuity Number of Eyes with an Improvement in acuity (average change in LogMar value) Total Rituximab 75% 1 (0.4) 2 1 (0.7) 4 Azathioprine 64% 5 (0.2) 7 2 (0.22) 14 Mycophenolate 50% 4 (0.24) 3 1 (0.2) 8 Dapsone 25% 3 (0.2) 1 0 4

Table 4: Outcomes for second drug treatment.