Parameters HCC
(n=15)
Adjacent
non-neoplastic liver tissue
P value
MIP-1a expression:
- (%)
+ (%)
++ (%)
+++ (%)
1 (6.7)
3 (20.0) 4 (26.7)
7 (46.7)
9 (60.0)
6 (40.0)
0 (0.0)
0 (0.0)
0.0004
CD68+ TAM count (/x400 field):
- Range
- Mean ± SD
28.7–108.7
73.47 ± 23.01
15.7–55.0
31.79 ± 11.55
<0.001
CD105-MVD (/x200 field):
- Range
- Mean ± SD
13.3-58.7
39.55 ± 12.55
5.7-21.0
13.05 ± 4.62
<0.001
- =<10% of cells are stained; + = 10-20 % of cells are positive; ++ = 20-50% of cells are positive; +++ = >50% of cells are positive.
Table 3: Macrophage Inflammatory Protein-1α (MIP-1α) expression, CD68-positive Tumour-Associated Macrophage (TAM) count and CD105-Micro Vessel Density (MVD) in Hepatocellular Carcinoma (HCC) and the adjacent non-neoplastic liver tissue.