Mutation Total (n=207) HCC (n=102) CH (n=105) P value OR (95% CI)
T1653  27 (13.0%) 18 (17.6%)  9 (8.5%) 0.088  
V1753  43 (29.5%) 43 (42.1%)* 18 (17.1%) 0.034 3.071 (1.68–5.86)
T1762/A1764 120 (57.9%) 66 (64.7%) 54 (51.4%) 0.802  
T1766  26 (25.5%) 19 (18.6%)*  7 (6.7%)  0.044 2.146 (0.96–7.12)
A1768  35 (16.9%) 26 (24.5%)*  9 (8.6%) 0.021 2.869 (1.21–6.49)
HCC: Hepatocellular Carcinoma; CH: Chronic Heptitis; OR: Odds Ratio; CI: Confidence Interval
*P<0.05 comparing the frequency of CP mutation in HCC vs.CH.
Table 2: Prevalence of mutations in the core promoter region between HCC and CH patients infected with HBV/C1.