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Figure 3: Embryonic-day specific effects of gestational ethanol exposure on fetal growth. Pregnant Long Evans rats were fed with isocaloric liquid diets containing 0% or 8.2% (v/v) ethanol. Diets were initiated at different embryonic days corresponding to stem cell activation (E6), appearance of secondary giant cells (E10), accumulation of glycogen cells (E14), and prior to (E15) or after (E16) trophoblast invasion into implantation site. (A) Fetuses were harvested and (B) body weights were determined on E19. Inter-group comparisons were made using ANOVA with Tukey’s multiple comparisons post-hoc test for statistical significance. N=3 dams per group (litter size varied from 7-to-14). |