Figure 4: Down-regulation of XB130 decreased cancer cell motility and invasion. A: Cell motility, average cells/field for 4 experiments ± S.E. (Materials and Methods). Each experiment consisted of three filters per cell line and 10 fields per filter were counted. B: Cell invasion through Matrigel, average cells per field for three experiments ± S.E. (Materials and Methods). Each experiment consisted of three filters per cell line and 10 fields per filter were counted. Significantly lower for the XB130 shRNA-transfected cell line compared to its parental cell line (Student’s t-test, *P< 0.05).