XB130 expression  
Clinicopathological features No. of cases Positive(+) Negative(-) p-value
Tissue       0.0001
Normal tissue 60 0(100%) 60(100%)  
Osteosarcoma tissue 60 24(40%) 36(60%)  
Age(year)       0.327
>20 19 7(36.8%) 12(63.2%)  
≤20 41 17(41.4%) 24(58.6%)  
Gender       0.486
Female 22 8(36.4%) 14(63.6%)  
Male 38 16(42.1%) 22(57.9%)  
Tumor metastasis       0.001
Yes 19 16(84.2%) 3(15.8%)  
No 41 8(19.5%) 33(80.5%)  
Size of primary OS(cm)       0.187
<8 28 9(32.1%) 19(67.9%)  
≥8 32 15(46.9%) 17(53.1%)  
Clinical stage       0.002
Ⅰ/ⅡA 23 4(17.4%) 19(82.6%)  
ⅡB/Ⅲ 37 20(54%) 17(46%)  
Histologic type       0.632
Osteoblastic 30 12(40%) 18(60%)  
Chondroblastic 11 5(45.4%) 6(54.6%)  
Fibroblastic 12 5(41.7%) 7(58.3%)  
Mixed 6 2(33.3%) 4(66.7%)  
Location       0.894
Femur 25 11(44%) 14(56%)  
Tibia 18 6(33.3%) 12(66.7%)  
Humurs 9 4(44.4%) 5(55.6%)  
Others 8 3(37.5%) 5(62.5%)  
Response to chemotherapy       0.086
Good 21 7(33.3%) 14(66.7%)  
Poor 39 17(43.6%) 22(56.4%)  
Table 1: Significance of the variables compared with the expression of XB130