|   
      
        |  | 95% Confidence |  
        | Variable | Hazard    ratio | Limits | p |  
        | Tumor    metastasis |  |  |  |  
        | No (n=41) | 1 | 1.453-5.824 | 0.0024 |  
        | Yes (n=19) | 2.762 |  
        | Size    of primary OS (cm) |  |  |  |  
        | <8 (n=28) | 1 | 1.620-5.219 | 0.02 |  
        | ≥8 (n=32) | 2.364 |  
        | Clinical    stage |  |  |  |  
        | Ⅰ/ⅡA (n=23) | 1 | 1.372-6.837 | 0.013 |  
        | ⅡB/Ⅲ (n=37) | 2.765 |  
        | Response    to chemotherapy |  |  |  |  
        | Poor (n=39) | 1 | 0.87-4.65 | 0.04 |  
        | Good (n=21) | 1.28 |  
        | XB130    expression |  |  |  |  
        | Low (n=36) | 1 | 1.47-5.36 | 0.01 |  
        | High (n=24) | 2.435 |  |