Figure 3: Equivocal (non-specific) asymmetric density. A 71 year old asymptomatic woman was called back from mammography screening for assessment of the non-specific asymmetric density on the mammograms of her right breast. Figures 3.A-D: Right and left breasts, mediolateral and craniocaudal projections. Subtle nonspecific (equivocal) asymmetric densities are seen in the upper-lateral portion of the right breast. Figure 3.E: Craniocaudal projection, microfocus magnification shows that the asymmetric densities correspond to several tiny stellate tumors that are scattered on an area measuring 4-6 cm. Figures 3.F,G: Breast MRI demonstrates the true extent of the disease. Left breast: no abnormality was demonstrable. Right breast: there are three malignant tumor foci in the upper central portion of the breast (10x9x9 mm, 5x4x4 mm, 4x4x3 mm). Morphology and kinetics of these lesions are characteristic for malignant tumor foci. Additional malignant tumor foci are seen in the upper portion of the breast. MRI extent of the disease: 76x29x46 mm. No pathologic lymph nodes in the axilla. Figures 3.H,I: Hand-held ultrasound of one of the tumor foci, also showing the biopsy needle. Figures 3.J-M: Large section histology and intermediate power histology images of the alveolar subtype of invasive lobular carcinoma, with multifocal well differentiated invasive lobular cancer (the largest focus measures 17x10 mm, the others are 6x5 mm and 4x4 mm) associated with extensive LCIS. Total disease extent: 80x30 mm. Biomarkers: ER/PR +ve, Her-2 -ve, Ki67 4%. No LVI. pN 0/2. LCIS on the resection margin toward the pectoral major muscle.