| Study |
Organ / Targeted tissue |
Detection |
CLE |
Sensitivity (%) |
Specificity (%) |
| Sharmaet al. [15] |
Esophagus Barrett’s |
HGD/EAC |
pCLE |
68.3 |
87.8 |
| Pech et al. [20]) |
Esophagus |
SCC |
eCLE |
100 |
87.0 |
| Li [23] |
Stomach |
Gastric neoplasia |
eCLE |
88.1 |
98.6 |
| Kiesslich et al.[26] |
Colon
Polyps and random sites |
Neoplasia |
eCLE |
97.4 |
99.4 |
| Hurlstone et al. [28] |
Colon
Polyps |
Neoplasia |
eCLE |
97.4 |
99.3 |
| Meining et al.[34] |
Colon
Polyps |
Neoplasia |
pCLE |
93 |
92 |
| Buchner et al.[34] |
Colon
Polyps |
Neoplasia |
pCLE |
91 |
76 |
| Meining et al.[49] |
Bile ducts Indeterminate
stricture |
Malignancy |
pCLE |
98 |
67 |
| Konda et al.[55] |
Pancreas
Cysts |
PCN |
nCLE |
59 |
100 |
|