Primary Cancer Number of patients Breast 8 Lung 2 Colon 2 Cervix 1 Carcinomatosis 1 Bile duct 1 Lymphoma 1 Kidney 1 Mesothelioma 1

Table 4: Advanced malignancy was judged to be the primary cause of AST and ALT enzyme alterations in 18 cases. Most of the patients had disseminated tumors and were treated with chemotherapy and/or radiation. Breast carcinoma accounted for nearly half of the 18 cases