Parameters |
Timolol maleate |
Bimatoprost |
Timolol maleate
degradate |
Bimatoprost
degradate |
Reference
values |
Resolution |
5.70 |
4.90 |
>1.5 |
Tailing factor (T) |
1.20 |
1.40 |
1.10 |
1.00 |
<1.5 |
Capacity factor (K) |
1.83 |
6.22 |
8.26 |
8.25 |
>1 |
Selectivity
(α) |
3.40 |
1.33 |
1.30 |
1-10 |
Theoretical plates(N) |
12641 |
11315 |
14532 |
10248 |
>3000 |
Retension time (min.) |
2.539 ± 0.01 |
7.224 ± 0.01 |
9.269 ± 0.01 |
13.892 ± 0.02 |
_ |
HETP |
0.0019 |
0.0022 |
0.0017 |
0.0024 |
Smaller the no., higher the efficiency |
|