Parameter
K
observed
(min
-1
)
t
1/2
(min)
t
90
(min)
Acid-induced degradation
60°C
0.0039
177.692
26.923
70°C
0.006
115.500
17.500
80°C
0.0087
79.655
12.069
Alkaline-induced degradation
60°C
0.0052
133.269
20.192
70°C
0.008
86.625
13.125
80°C
0.0102
67.941
10.294
Table 8:
Kinetic data of Pazufloxacin acidic and alkaline degradation in the presence of 1M HCl and 1M NaOH at different temperatures.
