Figure 1: (A) Schematic representation of α-syn peptide species. The α-syn peptides herewith studied correspond to 1-99 (syn1-99, blue), 1-52 (syn1- 52, pink), 57-102 (syn57-102, green) and 108-140 (syn108-140, red). At the N-terminal syn1-52 and syn57-102 have extra-sequence GSH and GSHM residues, respectively. (B) DHA-induced structural changes monitored by far- UV CD spectroscopy. (B) Ellipticity at 222 nm are plotted against the molar ratio between DHA and polypeptides. The analysis was conducted in PBS pH 7.4, using a peptide concentration of 5 μM. The titration curve of α-syn was also reported as reference.