| Method |
Gemifloxacin mesylate |
Theophylline |
Warfarin |
Omeprazole |
| Concentration (µg/ml) |
Recovery % |
CV % |
Concentration (µg/ml) |
Recovery % |
CV % |
Concentration (µg/ml) |
Recovery % |
CV % |
Concentration (µg/ml) |
Recovery % |
CV % |
| RP-HPLC |
0.05 |
90.000 |
6.667 |
0.25 |
90.000 |
5.333 |
0.1 |
87.000 |
8.046 |
0.1 |
87.000 |
9.195 |
| |
0.15 |
92.000 |
5.797 |
0.75 |
92.667 |
5.899 |
0.3 |
91.333 |
7.664 |
0.3 |
88.333 |
9.811 |
| |
1 |
89.500 |
2.570 |
4 |
89.800 |
2.840 |
2 |
87.050 |
3.561 |
1 |
90.400 |
6.416 |
| |
5 |
86.720 |
4.935 |
7 |
90.829 |
6.055 |
9 |
92.911 |
4.329 |
4 |
88.150 |
3.318 |
| TLC |
0.1 |
88.000 |
6.818 |
0.5 |
86.400 |
7.176 |
0.2 |
87.000 |
4.598 |
0.1 |
91.000 |
7.692 |
| |
0.3 |
88.333 |
3.396 |
1.5 |
93.000 |
4.659 |
0.6 |
88.667 |
4.323 |
0.3 |
87.000 |
4.215 |
| |
1.5 |
90.133 |
2.663 |
3 |
91.500 |
3.716 |
1 |
89.600 |
5.134 |
0.8 |
92.625 |
4.318 |
| |
2.5 |
93.400 |
2.484 |
5 |
85.300 |
7.550 |
2 |
91.050 |
5.052 |
1.2 |
93.583 |
5.788 |
CV%: Coefficient of Variation % |
