Gemifloxacin Theophylline Warfarin Omeprazole Proposed HPLC method Reported method (3) Proposed HPLC method Reported method (13) Proposed HPLC method Reported method (15) Proposed HPLC method Reported method (17) Mean 97.790 98.784 98.922 100.022 97.346 99.845 96.896 98.816 SD 1.1709 2.358 1.4535 1.5622 2.2999 2.6743 1.4392 2.8113 n 4 4 4 4 4 4 4 4 Variance 1.3710 5.5602 2.1127 2.4405 5.285 7.1519 2.0713 7.9034 t (2.447)* 1.11   1.03   1.42   1.85   F (9.28)* 4.056   1.155   1.352   3.816   * The values between parentheses are the corresponding theoretical values of t and F at the 95% confidence level.

Table 6: Statistical comparison between the results obtained by the proposed TLC method and the reported methods for the analysis of gemifloxacin, theophylline, warfarin and omeprazole in human plasma.