Figure 1: Chemical Structures of a- Amlodipine besylate b- Atorvastatin calcium c- Losartan potassium d- Valsartan Amlodipine besylate is 3-Ethyl 5-methyl (4RS)-2-[(2-aminoethoxy) methyl]- 4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate benzene sulphonate. Atorvastatin calcium is R-(βR,δR)]-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1- methylethyl)-3-phenyl-4-[(phenylamino) carbonyl]-1Hpyrrole-1-heptanoic acid, calcium salt (2:1) trihydrate Losartan Potassium is 1H-Imidazole-5-methanol,2-butyl-4-chloro-1-[[2'-(lH -tetrazol-5-yl) [1,1'-biphenyl]-4-yl] methyl] monopotassium salt. Valsartan is N-(1-oxopentyl)-N-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl] methyl]-L-valine.