Drug name Recovery  ±  SD Calculated t- values Calculated F- values Proposed methods Reference method Brimonidine Tartrate 101.41 ± 0.95 100.85 ± 1.00 2.49 0.94 Timolol Maleate 101.40 ± 1.32 101.23 ± 1.16 1.13 1.28 (Where the Tabulated t-values and F -ratios at p= 0.05 are 2.57 and 5.05)

Table 3: Statistical comparison of the proposed and published methods for determination of Brimonidine Tartrate and Timolol Maleate respectively in their dosage forms by reported method (T- student test) and (F–test for variance).